Evolutionary Biology

Masculinization of the X-chromosome in aphid soma and gonads

10.24072/pcjournal.166 - Peer Community Journal, Volume 2 (2022), article no. e53.

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Males and females share essentially the same genome but differ in their optimal values for many phenotypic traits, which can result in intra-locus conflict between the sexes. Aphids display XX/X0 sex chromosomes and combine unusual X chromosome inheritance with cyclical parthenogenesis. Theoretical and empirical works support the hypothesis that the large excess of male-biased genes observed on the aphid X chromosome compared to autosomes evolved in response to sexual conflicts, by restricting the products of sexually antagonistic alleles to the sex they benefits. However, whether such masculinization of the X affects all tissues (as expected if it evolved in response to sexual conflicts) or is limited to specific tissues remains an open question. Here, we measured gene expression in three different somatic and gonadic tissues of males, sexual females and parthenogenetic females of the pea aphid. We observed a masculinization of the X in each of the studied tissues, with male-biased genes being 2.5 to 3.5 more frequent on the X than expected. We also tested the hypothesis that gene duplication can facilitate the attenuation of conflicts by allowing gene copies to neo- or sub-functionalize and reach sex-specific optima. As predicted, X-linked copies of duplicated genes having their other copies on autosomes were more frequently male-biased (40.5% of the genes) than duplicated autosomal genes (6.6%) or X-linked single-copy genes (32.5%). These results highlight a peculiar pattern of expression of X-linked genes in aphids at the tissue level and provide further support for sex-biased expression as a mechanism to attenuate intra-locus sexual conflicts.

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DOI: 10.24072/pcjournal.166
Jaquiéry, Julie 1; Simon, Jean-Christophe 1; Robin, Stéphanie 1, 2; Richard, Gautier 1; Peccoud, Jean 3; Boulain, Hélène 4; Legeai, Fabrice 1, 2; Tanguy, Sylvie 1; Prunier-Leterme, Nathalie 1; Letrionnaire, Gaël 1

1 INRAE, UMR 1349, Institute of Genetics, Environment and Plant Protection - Le Rheu, France
2 University of Rennes, CNRS, Inria, IRISA, UMR 6074 - Rennes, France
3 Laboratoire Ecologie et Biologie des Interactions, Equipe Ecologie Evolution Symbiose, UMR CNRS 7267, Université de Poitiers - Poitiers, France
4 Department of Ecology and Evolution, University of Lausanne - Lausanne, Switzerland
License: CC-BY 4.0
Copyrights: The authors retain unrestricted copyrights and publishing rights
     author = {Jaqui\'ery, Julie and Simon, Jean-Christophe and Robin, St\'ephanie and Richard, Gautier and Peccoud, Jean and Boulain, H\'el\`ene and Legeai, Fabrice and Tanguy, Sylvie and Prunier-Leterme, Nathalie and Letrionnaire, Ga\"el},
     title = {Masculinization of the {X-chromosome} in aphid soma and gonads},
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Jaquiéry, Julie; Simon, Jean-Christophe; Robin, Stéphanie; Richard, Gautier; Peccoud, Jean; Boulain, Hélène; Legeai, Fabrice; Tanguy, Sylvie; Prunier-Leterme, Nathalie; Letrionnaire, Gaël. Masculinization of the X-chromosome in aphid soma and gonads. Peer Community Journal, Volume 2 (2022), article  no. e53. doi : 10.24072/pcjournal.166. https://peercommunityjournal.org/articles/10.24072/pcjournal.166/

Peer reviewed and recommended by PCI : 10.24072/pci.evolbiol.100148

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