Section: Infections
Topic: Biology of interactions, Genetics/Genomics

Transcriptome responses of the aphid vector Myzus persicae are shaped by identities of the host plant and the virus

10.24072/pcjournal.208 - Peer Community Journal, Volume 2 (2022), article no. e82.

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Background: Numerous studies have documented modifications in vector orientation behavior, settling and feeding behavior, and/or fecundity and survival due to virus infection in host plants. These alterations are often expected to enhance virus transmission, which has led to the hypothesis that such effects are vector manipulations by the virus. However, until now, the gene expression changes correlating with these effects and indicative of modified vector pathways and mechanisms are mostly unknown.

Results: Transcriptome profiling of Myzus persicae aphids feeding on turnip yellows virus (TuYV) and cauliflower mosaic virus (CaMV) infected Arabidopsis thaliana and Camelina sativa revealed a substantial proportion of commonly deregulated genes, amongst them many with general functions in plant-virus-aphid interactions. We identified also aphid genes specifically deregulated by CaMV or TuYV infection, which might be related to the viral transmission mode. Furthermore, we observed strong host-specific differences in the gene expression patterns with plant virus infection causing more deregulations of aphid genes on A. thaliana than on C. sativa, likely related to the differences in susceptibility of the plant hosts to these viruses. Finally, stress-related aphid genes were downregulated in M. persicae on both infected plants, regardless of the virus.

Conclusions: TuYV, relying on the circulative persistent mode of transmission, tended to affect developmental genes. This could increase the proportion of alate aphids, but also affect their locomotion, neuronal activity, and lifespan. CaMV, using the non-circulative non-persistent mode of transmission, had a strong impact on feeding-related genes and in particular those related to salivary proteins. In general, these transcriptome alterations targeted pathways that seem to be particularly adapted to the transmission mode of the corresponding virus and could be evidence of vector manipulation by the virus.

Published online:
DOI: 10.24072/pcjournal.208
Type: Research article

Chesnais, Quentin 1; Golyaev, Victor 2; Velt, Amandine 1; Rustenholz, Camille 1; Verdier, Maxime 1; Brault, Véronique 1; Pooggin, Mikhail M 2; Drucker, Martin 1

1 SVQV, UMR1131, INRAE Centre Grand Est – Colmar, Université Strasbourg, France
2 PHIM, Plant Health Institute, University of Montpellier, INRAE, CIRAD, IRD, Institute Agro, Montpellier, France
License: CC-BY 4.0
Copyrights: The authors retain unrestricted copyrights and publishing rights
     author = {Chesnais, Quentin and Golyaev, Victor and Velt, Amandine and Rustenholz, Camille and Verdier, Maxime and Brault, V\'eronique and Pooggin, Mikhail M and Drucker, Martin},
     title = {Transcriptome responses of the aphid vector {\protect\emph{Myzus} persicae} are shaped by identities of the host plant and the virus},
     journal = {Peer Community Journal},
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     publisher = {Peer Community In},
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     year = {2022},
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%A Golyaev, Victor
%A Velt, Amandine
%A Rustenholz, Camille
%A Verdier, Maxime
%A Brault, Véronique
%A Pooggin, Mikhail M
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Chesnais, Quentin; Golyaev, Victor; Velt, Amandine; Rustenholz, Camille; Verdier, Maxime; Brault, Véronique; Pooggin, Mikhail M; Drucker, Martin. Transcriptome responses of the aphid vector Myzus persicae are shaped by identities of the host plant and the virus. Peer Community Journal, Volume 2 (2022), article  no. e82. doi : 10.24072/pcjournal.208.

PCI peer reviews and recommendation, and links to data, scripts, code and supplementary information: 10.24072/pci.infections.100006

Conflict of interest of the recommender and peer reviewers:
The recommender in charge of the evaluation of the article and the reviewers declared that they have no conflict of interest (as defined in the code of conduct of PCI) with the authors or with the content of the article.

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