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Section: Health & Movement Sciences
Topic: Health sciences, Neuroscience

Interlimb coordination in Parkinson’s Disease is minimally affected by a visuospatial dual task

Hill, Allen1 ; Nantel, Julie1
1 School of Human Kinetics, University of Ottawa - Ottawa, Canada

10.24072/pcjournal.387 - Peer Community Journal, Volume 4 (2024), article no. e31.

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Parkinson’s disease (PD) leads to reduced spatial and temporal interlimb coordination during gait as well as reduced coordination in the upper or lower limbs. Multi-tasking when walking is common during real-world activities, and affects some gait characteristics, like gait speed and variability. However, the impact of a dual task (DT) on intra and interlimb coordination of both lower and upper limbs when walking in people with PD remains unknown. Seventeen volunteers with mild to moderate PD (11 males, 65 ± 8 years, 173 ± 8 cm, 74 ± 20 kg, Unified Parkinson’s Disease Rating Scale motor section 10 ± 5) participated in gait trials in an Extended-CAREN system, which includes a treadmill, 12-camera Vicon motion capture system, and a 180° field-of-view virtual reality projection screen. Participants completed a 3 min walking trial and a 2 min visuospatial word recognition DT trial at their preferred walking pace. Single and DT were compared with a paired t-test, and the less and more affected (LA, MA) sides were tested for equivalence in sensitivity to the DT. During the DT, we found the LA shoulder ROM decreased by 1.5°, and the LA shoulder peak flexion decreased by 1.1° (p<.028, gav>.12). The LA and MA hip ROM were differently affected by the dual task (p=.023), and intralimb coordination was affected by dual tasking equivalently between sides (p=.004). These results suggest that during normal single-task gait, people with PD use attentional resources to compensate for reduced arm swing. Furthermore, our results indicate that any effect of DT on lower intralimb coordination is not meaningfully different between the LA and MA sides.

Published online:
DOI: 10.24072/pcjournal.387
Type: Research article
Keywords: Parkinson’s disease, dual task, interlimb coordination, relative phase, more affected side
Hill, Allen 1; Nantel, Julie 1

1 School of Human Kinetics, University of Ottawa - Ottawa, Canada
License: CC-BY 4.0
Copyrights: The authors retain unrestricted copyrights and publishing rights
Web-published in collaboration with: UGA Éditions
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Hill, Allen; Nantel, Julie. Interlimb coordination in Parkinson’s Disease is minimally affected by a visuospatial dual task. Peer Community Journal, Volume 4 (2024), article  no. e31. doi : 10.24072/pcjournal.387. https://peercommunityjournal.org/articles/10.24072/pcjournal.387/

PCI peer reviews and recommendation, and links to data, scripts, code and supplementary information: 10.24072/pci.healthmovsci.100043

Conflict of interest of the recommender and peer reviewers:
The recommender in charge of the evaluation of the article and the reviewers declared that they have no conflict of interest (as defined in the code of conduct of PCI) with the authors or with the content of the article.

[1] Ahmadi, S.; Siragy, T.; Nantel, J. Regularity of kinematic data between single and dual-task treadmill walking in people with Parkinson’s disease, Journal of NeuroEngineering and Rehabilitation, Volume 18 (2021) no. 1, p. 20 | DOI

[2] Al-Yahya, E.; Dawes, H.; Smith, L.; Dennis, A.; Howells, K.; Cockburn, J. Cognitive motor interference while walking: A systematic review and meta-analysis, Neuroscience & Biobehavioral Reviews, Volume 35 (2011) no. 3, pp. 715-728 | DOI

[3] Almeida, Q. J.; Brown, M. J. N. Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?, Frontiers in Neurology, Volume 4 (2013) | DOI

[4] Barak, Y.; Wagenaar, R. C.; Holt, K. G. Gait Characteristics of Elderly People With a History of Falls: A Dynamic Approach, Physical Therapy, Volume 86 (2006) no. 11, pp. 1501-1510 | DOI

[5] Barela, J. A.; Whitall, J.; Black, P.; Clark, J. E. An examination of constraints affecting the intralimb coordination of hemiparetic gait, Human Movement Science, Volume 19 (2000) no. 2, pp. 251-273 | DOI

[6] Baron, E. I.; Miller Koop, M.; Streicher, M. C.; Rosenfeldt, A. B.; Alberts, J. L. Altered kinematics of arm swing in Parkinson's disease patients indicates declines in gait under dual-task conditions, Parkinsonism & Related Disorders, Volume 48 (2018), pp. 61-67 | DOI

[7] Bekkers, E. M. J.; Dockx, K.; Devan, S.; Van Rossom, S.; Verschueren, S. M. P.; Bloem, B. R.; Nieuwboer, A. The Impact of Dual-Tasking on Postural Stability in People With Parkinson’s Disease With and Without Freezing of Gait, Neurorehabilitation and Neural Repair, Volume 32 (2018) no. 2, pp. 166-174 | DOI

[8] Bezanson, J.; Edelman, A.; Karpinski, S.; Shah, V. Julia: A Fresh Approach to Numerical Computing, SIAM Review, Volume 59 (2017) no. 1, pp. 65-98 | DOI

[9] Byrne, J. E.; Stergiou, N.; Blanke, D.; Houser, J. J.; Kurz, M. J.; Hageman, P. A. Comparison of Gait Patterns between Young and Elderly Women: An Examination of Coordination, Perceptual and Motor Skills, Volume 94 (2002) no. 1, pp. 265-280 | DOI

[10] Cumming, G. Understanding The New Statistics, Routledge, New York, 2011 | DOI

[11] Delp, S. L.; Anderson, F. C.; Arnold, A. S.; Loan, P.; Habib, A.; John, C. T.; Guendelman, E.; Thelen, D. G. OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement, IEEE Transactions on Biomedical Engineering, Volume 54 (2007) no. 11, pp. 1940-1950 | DOI

[12] Djaldetti, R.; Ziv, I.; Melamed, E. The mystery of motor asymmetry in Parkinson's disease, The Lancet Neurology, Volume 5 (2006) no. 9, pp. 796-802 | DOI

[13] Fasano, A.; Schlenstedt, C.; Herzog, J.; Plotnik, M.; Rose, F. E. M.; Volkmann, J.; Deuschl, G. Split-belt locomotion in Parkinson's disease links asymmetry, dyscoordination and sequence effect, Gait & Posture, Volume 48 (2016), pp. 6-12 | DOI

[14] Faul, F.; Erdfelder, E.; Lang, A.-G.; Buchner, A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences, Behavior Research Methods, Volume 39 (2007) no. 2, pp. 175-191 | DOI

[15] Fisher, N. I. Statistical Analysis of Circular Data, Cambridge University Press, 1993 | DOI

[16] Gelman, A.; Stern, H. The Difference Between “Significant” and “Not Significant” is not Itself Statistically Significant, The American Statistician, Volume 60 (2006) no. 4, pp. 328-331 | DOI

[17] Ghanavati, T.; Salavati, M.; Karimi, N.; Negahban, H.; Ebrahimi Takamjani, I.; Mehravar, M.; Hessam, M. Intra-limb coordination while walking is affected by cognitive load and walking speed, Journal of Biomechanics, Volume 47 (2014) no. 10, pp. 2300-2305 | DOI

[18] Haken, H.; Kelso, J. A. S.; Bunz, H. A theoretical model of phase transitions in human hand movements, Biological Cybernetics, Volume 51 (1985) no. 5, pp. 347-356 | DOI

[19] Hill, A.; Nantel, J. Data and Code for: Interlimb coordination in Parkinson's Disease is minimally affected by a visuospatial dual task, Zenodo, 2023 | DOI

[20] Hillel, I.; Gazit, E.; Nieuwboer, A.; Avanzino, L.; Rochester, L.; Cereatti, A.; Croce, U. D.; Rikkert, M. O.; Bloem, B. R.; Pelosin, E.; Del Din, S.; Ginis, P.; Giladi, N.; Mirelman, A.; Hausdorff, J. M. Is every-day walking in older adults more analogous to dual-task walking or to usual walking? Elucidating the gaps between gait performance in the lab and during 24/7 monitoring, European Review of Aging and Physical Activity, Volume 16 (2019) no. 1, p. 6 | DOI

[21] Huang, X.; Mahoney, J. M.; Lewis, M. M.; Du, G.; Piazza, S. J.; Cusumano, J. P. Both coordination and symmetry of arm swing are reduced in Parkinson's disease, Gait & Posture, Volume 35 (2012) no. 3, pp. 373-377 | DOI

[22] Isaias, I. U.; Volkmann, J.; Marzegan, A.; Marotta, G.; Cavallari, P.; Pezzoli, G. The Influence of Dopaminergic Striatal Innervation on Upper Limb Locomotor Synergies, PLOS ONE, Volume 7 (2012) no. 12, p. e51464 | DOI

[23] Jankovic, J. Motor fluctuations and dyskinesias in Parkinson's disease: Clinical manifestations, Movement Disorders, Volume 20 (2005) no. S11, p. S11-S16 | DOI

[24] Killeen, T.; Elshehabi, M.; Filli, L.; Hobert, M. A.; Hansen, C.; Rieger, D.; Brockmann, K.; Nussbaum, S.; Zörner, B.; Bolliger, M.; Curt, A.; Berg, D.; Maetzler, W. Arm swing asymmetry in overground walking, Scientific Reports, Volume 8 (2018) no. 1, p. 12803 | DOI

[25] Krasovsky, T.; Baniña, M. C.; Hacmon, R.; Feldman, A. G.; Lamontagne, A.; Levin, M. F. Stability of gait and interlimb coordination in older adults, Journal of Neurophysiology, Volume 107 (2012) no. 9, pp. 2560-2569 | DOI

[26] Krasovsky, T.; Levin, M. F. Review: Toward a Better Understanding of Coordination in Healthy and Poststroke Gait, Neurorehabilitation and Neural Repair, Volume 24 (2010) no. 3, pp. 213-224 | DOI

[27] Lakens, D. Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs, Frontiers in Psychology, Volume 4 (2013) | DOI

[28] Lakens, D. Equivalence Tests: A Practical Primer for t Tests, Correlations, and Meta-Analyses, Social Psychological and Personality Science, Volume 8 (2017) no. 4, pp. 355-362 | DOI

[29] Lamb, P. F.; Stöckl, M. On the use of continuous relative phase: Review of current approaches and outline for a new standard, Clinical Biomechanics, Volume 29 (2014) no. 5, pp. 484-493 | DOI

[30] Marigold, D. S.; Misiaszek, J. E. Whole-Body Responses: Neural Control and Implications for Rehabilitation and Fall Prevention, The Neuroscientist, Volume 15 (2009) no. 1, pp. 36-46 | DOI

[31] Mirelman, A.; Bernad‐Elazari, H.; Thaler, A.; Giladi‐Yacobi, E.; Gurevich, T.; Gana‐Weisz, M.; Saunders‐Pullman, R.; Raymond, D.; Doan, N.; Bressman, S. B.; Marder, K. S.; Alcalay, R. N.; Rao, A. K.; Berg, D.; Brockmann, K.; Aasly, J.; Waro, B. J.; Tolosa, E.; Vilas, D.; Pont‐Sunyer, C.; Orr‐Urtreger, A.; Hausdorff, J. M.; Giladi, N. Arm swing as a potential new prodromal marker of Parkinson's disease, Movement Disorders, Volume 31 (2016) no. 10, pp. 1527-1534 | DOI

[32] Mirelman, A.; Bonato, P.; Camicioli, R.; Ellis, T. D.; Giladi, N.; Hamilton, J. L.; Hass, C. J.; Hausdorff, J. M.; Pelosin, E.; Almeida, Q. J. Gait impairments in Parkinson's disease, The Lancet Neurology, Volume 18 (2019) no. 7, pp. 697-708 | DOI

[33] Nanhoe-Mahabier, W.; Snijders, A. H.; Delval, A.; Weerdesteyn, V.; Duysens, J.; Overeem, S.; Bloem, B. R. Walking patterns in Parkinson's disease with and without freezing of gait, Neuroscience, Volume 182 (2011), pp. 217-224 | DOI

[34] Park, K.; Roemmich, R. T.; Elrod, J. M.; Hass, C. J.; Hsiao-Wecksler, E. T. Effects of aging and Parkinson's disease on joint coupling, symmetry, complexity and variability of lower limb movements during gait, Clinical Biomechanics, Volume 33 (2016), pp. 92-97 | DOI

[35] Plate, A.; Sedunko, D.; Pelykh, O.; Schlick, C.; Ilmberger, J. R.; Bötzel, K. Normative data for arm swing asymmetry: How (a)symmetrical are we?, Gait & Posture, Volume 41 (2015) no. 1, pp. 13-18 | DOI

[36] Plotnik, M.; Giladi, N.; Hausdorff, J. M. Bilateral coordination of gait and Parkinson’s disease: the effects of dual tasking, Journal of Neurology, Neurosurgery & Psychiatry, Volume 80 (2009) no. 3, pp. 347-350 | DOI

[37] Plotnik, M.; Dagan, Y.; Gurevich, T.; Giladi, N.; Hausdorff, J. M. Effects of cognitive function on gait and dual tasking abilities in patients with Parkinson’s disease suffering from motor response fluctuations, Experimental Brain Research, Volume 208 (2011) no. 2, pp. 169-179 | DOI

[38] Plotnik, M.; Giladi, N.; Dagan, Y.; Hausdorff, J. M. Postural instability and fall risk in Parkinson’s disease: impaired dual tasking, pacing, and bilateral coordination of gait during the “ON” medication state, Experimental Brain Research, Volume 210 (2011) no. 3, pp. 529-538 | DOI

[39] Plotnik, M.; Giladi, N.; Hausdorff, J. M. A new measure for quantifying the bilateral coordination of human gait: effects of aging and Parkinson’s disease, Experimental Brain Research, Volume 181 (2007) no. 4, pp. 561-570 | DOI

[40] Plotnik, M.; Hausdorff, J. M. The role of gait rhythmicity and bilateral coordination of stepping in the pathophysiology of freezing of gait in Parkinson's disease, Movement Disorders, Volume 23 (2008) no. S2, p. S444-S450 | DOI

[41] Poewe, W.; Seppi, K.; Tanner, C. M.; Halliday, G. M.; Brundin, P.; Volkmann, J.; Schrag, A.-E.; Lang, A. E. Parkinson disease, Nature Reviews Disease Primers, Volume 3 (2017), p. 17013 | DOI

[42] Rajagopal, A.; Dembia, C. L.; DeMers, M. S.; Delp, D. D.; Hicks, J. L.; Delp, S. L. Full-Body Musculoskeletal Model for Muscle-Driven Simulation of Human Gait, IEEE Transactions on Biomedical Engineering, Volume 63 (2016) no. 10, pp. 2068-2079 | DOI

[43] Ravi, D. A recommendation of ‘Interlimb coordination in Parkinson’s Disease is minimally affected by a visuospatial dual task’, Peer Community In Health and Movement Sciences (2024) | DOI

[44] Ribeiro, T. S.; Sousa, d. A. C.; Lucena, d. L. C.; Santiago, L. M. M.; Lindquist, A. R. R. Does dual task walking affect gait symmetry in individuals with Parkinson’s disease?, European Journal of Physiotherapy, Volume 21 (2019) no. 1, pp. 8-14 | DOI

[45] Ricciardi, L.; Ricciardi, D.; Lena, F.; Plotnik, M.; Petracca, M.; Barricella, S.; Bentivoglio, A. R.; Modugno, N.; Bernabei, R.; Fasano, A. Working on asymmetry in Parkinson’s disease: randomized, controlled pilot study, Neurological Sciences, Volume 36 (2015) no. 8, pp. 1337-1343 | DOI

[46] Rochester, L.; Galna, B.; Lord, S.; Burn, D. The nature of dual-task interference during gait in incident Parkinson’s disease, Neuroscience, Volume 265 (2014), pp. 83-94 | DOI

[47] Roemmich, R. T.; Field, A. M.; Elrod, J. M.; Stegemöller, E. L.; Okun, M. S.; Hass, C. J. Interlimb coordination is impaired during walking in persons with Parkinson's disease, Clinical Biomechanics, Volume 28 (2013) no. 1, pp. 93-97 | DOI

[48] Roemmich, R. T.; Nocera, J. R.; Stegemöller, E. L.; Hassan, A.; Okun, M. S.; Hass, C. J. Locomotor adaptation and locomotor adaptive learning in Parkinson’s disease and normal aging, Clinical Neurophysiology, Volume 125 (2014) no. 2, pp. 313-319 | DOI

[49] Roerdink, M.; Coolen, B. (.; Clairbois, B. (.; Lamoth, C. J.; Beek, P. J. Online gait event detection using a large force platform embedded in a treadmill, Journal of Biomechanics, Volume 41 (2008) no. 12, pp. 2628-2632 | DOI

[50] Roggendorf, J.; Chen, S.; Baudrexel, S.; van de Loo, S.; Seifried, C.; Hilker, R. Arm swing asymmetry in Parkinson's disease measured with ultrasound based motion analysis during treadmill gait, Gait & Posture, Volume 35 (2012) no. 1, pp. 116-120 | DOI

[51] Sadeghi, H.; Allard, P.; Prince, F.; Labelle, H. Symmetry and limb dominance in able-bodied gait: a review, Gait & Posture, Volume 12 (2000) no. 1, pp. 34-45 | DOI

[52] Shaaban, H.; Pereira, C.; Williams, R.; Lees, V. C. The Effect Of Elbow Position On The Range Of Supination And Pronation Of The Forearm, Journal of Hand Surgery (European Volume), Volume 33 (2008) no. 1, pp. 3-8 | DOI

[53] Shishov, N.; Gimmon, Y.; Rashed, H.; Kurz, I.; Riemer, R.; Shapiro, A.; Debi, R.; Melzer, I. Old adult fallers display reduced flexibility of arm and trunk movements when challenged with different walking speeds, Gait & Posture, Volume 52 (2017), pp. 280-286 | DOI

[54] Siragy, T.; Nantel, J. Absent Arm Swing and Dual Tasking Decreases Trunk Postural Control and Dynamic Balance in People With Parkinson's Disease, Frontiers in Neurology, Volume 11 (2020) | DOI

[55] Sterling, N. W.; Cusumano, J. P.; Shaham, N.; Piazza, S. J.; Liu, G.; Kong, L.; Du, G.; Lewis, M. M.; Huang, X. Dopaminergic modulation of arm swing during gait among Parkinson’s disease patients, Journal of Parkinson's disease, Volume 5 (2015) no. 1, pp. 141-150 | DOI

[56] Temprado, J.-J.; Zanone, P.-G.; Monno, A.; Laurent, M. Attentional load associated with performing and stabilizing preferred bimanual patterns, Journal of Experimental Psychology: Human Perception and Performance, Volume 25 (1999) no. 6, pp. 1579-1594 | DOI

[57] Wagenaar, R.; van Emmerik, R. Resonant frequencies of arms and legs identify different walking patterns, Journal of Biomechanics, Volume 33 (2000) no. 7, pp. 853-861 | DOI

[58] Wilken, J. M.; Rodriguez, K. M.; Brawner, M.; Darter, B. J. Reliability and minimal detectible change values for gait kinematics and kinetics in healthy adults, Gait & Posture, Volume 35 (2012) no. 2, pp. 301-307 | DOI

[59] Williams, A. J.; Peterson, D. S.; Earhart, G. M. Gait coordination in Parkinson disease: Effects of step length and cadence manipulations, Gait & Posture, Volume 38 (2013) no. 2, pp. 340-344 | DOI

[60] Winogrodzka, A.; Wagenaar, R. C.; Booij, J.; Wolters, E. C. Rigidity and bradykinesia reduce interlimb coordination in Parkinsonian gait, Archives of Physical Medicine and Rehabilitation, Volume 86 (2005) no. 2, pp. 183-189 | DOI

[61] Winter, D. A. Biomechanics and Motor Control of Human Movement, John Wiley & Sons, Inc., Hoboken, New Jersey, 2009 | DOI

[62] Yarnall, A.; Rochester, L.; Burn, D. J. The interplay of cholinergic function, attention, and falls in Parkinson's disease, Movement Disorders, Volume 26 (2011) no. 14, pp. 2496-2503 | DOI

[63] Yogev, G.; Plotnik, M.; Peretz, C.; Giladi, N.; Hausdorff, J. M. Gait asymmetry in patients with Parkinson’s disease and elderly fallers: when does the bilateral coordination of gait require attention?, Experimental Brain Research, Volume 177 (2007) no. 3, pp. 336-346 | DOI

[64] Yogev‐Seligmann, G.; Hausdorff, J. M.; Giladi, N. The role of executive function and attention in gait, Movement Disorders, Volume 23 (2008) no. 3, pp. 329-342 | DOI

[65] van Emmerik, R.; Wagenaar, R. Dynamics of movement coordination and tremor during gait in Parkinson's disease, Human Movement Science, Volume 15 (1996) no. 2, pp. 203-235 | DOI

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