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Section: Mathematical & Computational Biology
Topic:
Evolution,
Genetics/genomics
Genetic Evidence for Geographic Structure within the Neanderthal Population
10.24072/pcjournal.448 - Peer Community Journal, Volume 4 (2024), article no. e68.
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PSMC estimates of Neanderthal effective population size (Ne) exhibit a roughly 5-fold decline across the most recent 20~ky before the death of each fossil. To explain this pattern, this article develops new theory relating genetic variation to geographic population structure and local extinction. It argues that the observed pattern results from subdivision and gene flow. If two haploid genomes are sampled from the same subpopulation, their recent ancestors are likely to be geographic neighbors and therefore coalesce rapidly. By contrast, remote ancestors are likely to be far apart, and their coalescent rate is lower. Consequently, Ne is larger in the distant past than in the recent past. New theoretical results show that modest rates of extinction cause substantial reductions in heterozygosity, Wright's FST, and Ne.
Type: Research article
Rogers, Alan R. 1
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@article{10_24072_pcjournal_448, author = {Rogers, Alan R.}, title = {Genetic {Evidence} for {Geographic} {Structure} within the~ {Neanderthal} {Population}}, journal = {Peer Community Journal}, eid = {e68}, publisher = {Peer Community In}, volume = {4}, year = {2024}, doi = {10.24072/pcjournal.448}, language = {en}, url = {https://peercommunityjournal.org/articles/10.24072/pcjournal.448/} }
TY - JOUR AU - Rogers, Alan R. TI - Genetic Evidence for Geographic Structure within the Neanderthal Population JO - Peer Community Journal PY - 2024 VL - 4 PB - Peer Community In UR - https://peercommunityjournal.org/articles/10.24072/pcjournal.448/ DO - 10.24072/pcjournal.448 LA - en ID - 10_24072_pcjournal_448 ER -
%0 Journal Article %A Rogers, Alan R. %T Genetic Evidence for Geographic Structure within the Neanderthal Population %J Peer Community Journal %D 2024 %V 4 %I Peer Community In %U https://peercommunityjournal.org/articles/10.24072/pcjournal.448/ %R 10.24072/pcjournal.448 %G en %F 10_24072_pcjournal_448
Rogers, Alan R. Genetic Evidence for Geographic Structure within the Neanderthal Population. Peer Community Journal, Volume 4 (2024), article no. e68. doi : 10.24072/pcjournal.448. https://peercommunityjournal.org/articles/10.24072/pcjournal.448/
PCI peer reviews and recommendation, and links to data, scripts, code and supplementary information: 10.24072/pci.mcb.100232
Conflict of interest of the recommender and peer reviewers:
The recommender in charge of the evaluation of the article and the reviewers declared that they have no conflict of interest (as defined in the code of conduct of PCI) with the authors or with the content of the article.
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